From Wikipedia: Caroline Earle White (1833–1916) was an American philanthropist and anti-vivisection
activist. She co-founded the Pennsylvania Society for the Prevention of
Cruelty to Animals (PSPCA) in 1867, founded its women's branch (WPSPCA)
in 1869, and founded the American Anti-Vivisection Society
I heard a story about Caroline Earle White this morning on NPR. You can see some photos and the interview here.